Chemical Methodologies

Original Article

Voltammetric Sensor for Acyclovir Determination Based on MoSe2/rGO Nanocomposite Modified Electrode

Somayeh Tajik; Fariba Garkani Nejad; Reza Zaimbashi; Hadi Beitollai

Articles in Press, Accepted Manuscript, Available Online from 14 April 2024

https://doi.org/10.48309/chemm.2024.444547.1771

Abstract

In this study, MoSe2/rGO nanocomposite modified screen printed graphite electrode (SPGE) was designed for acyclovir (ACV) determination. The electrochemical investigation and measurement ... Read More

Original Article

Synthesis, Molecular Docking, and Anticancer Evaluation of New Azo-Based Sulfonamides against MCF 7 Human Breast Cancer Cell Line

Olia Rezaeianzadeh; Sakineh Asghari; Mahmood Tajbakhsh; Mojtaba Mohseni; Asieh Khalilpour

Articles in Press, Accepted Manuscript, Available Online from 30 April 2024

https://doi.org/10.48309/chemm.2024.447205.1773

Abstract

We synthesized a series of new azo-based sulfonamides 8a-l via multistep chemical processes including chlorosulfonation, nucleophilic substitution, diazotization, and coupling reactions. ... Read More

Original Article

Zinc Alginate Beads as an Effective Biosorbent for the Removal of Eosin-B from Aquatic Solutions: Equilibrium, Kinetics, and Thermodynamic Behaviors

Mohsen Samimi; Khadijeh Amiri

Articles in Press, Accepted Manuscript, Available Online from 07 May 2024

https://doi.org/10.48309/chemm.2024.454717.1791

Abstract

Spherical alginate-based hydrogels have been applied for environmental pollutants removal from aqueous solutions. In this study, zinc alginate beads were prepared using an ionotropic ... Read More

Original Article

Chemical Composition, Antioxidant Properties, and Antimicrobial Activity of Ferula Assa-foetida L. Essential Oil against Pathogenic Bacteria

Tahereh Sangchooli; Sobhan Aboulhassanzadeh; Hamed Aghazadeh; Marzieh Paeizi; Dariush Shokri; Maryam Malekzadeh

Articles in Press, Accepted Manuscript, Available Online from 11 May 2024

https://doi.org/10.48309/chemm.2024.451953.1780

Abstract

Ferula assa-foetida L. (Asafoetida) a medicinal plant with antimicrobial and antioxidant properties, is crucial in the food and pharmaceutical industries. Ferula essential oils (EOs), ... Read More Ferula assa-foetida L. (Asafoetida) a medicinal plant with antimicrobial and antioxidant properties, is crucial in the food and pharmaceutical industries. Ferula essential oils (EOs), rich in ferulic acid, flavonoids, alkaloids, and glycosides compositions, may offer a potential solution to antibiotic resistance. The aim of this work is to investigate the components of Ferula chemical essential oil (EO) and its antioxidant and antimicrobial properties in different habitats of Iran (Tabas, Yazd, Neishabur, and Kerman). Gas Chromatography-Mass Spectrometry (GC-MS) analysis was performed to determine the composition of the essential oils from the four different sources. The antimicrobial activity, the minimum inhibitory concentration (MIC), and the minimum bactericidal concentration (MBC) of the essential oils against both Gram-positive and Gram-negative pathogenic bacteria were evaluated using the broth microdilution method and the well diffusion test. Likewise, the antioxidant properties of the essential oils were examined using the DPPH radical scavenging method. GC-MS analysis identified the major components of the essential oils, with the Nishabur EO having the highest percentage of components. The Kerman EO had the lowest inhibitory concentration against Escherichia coli, at 6.25 mg/ml, while the Yazd EO demonstrated the highest inhibitory concentration against Staphylococcus aureus, at a minimum inhibitory concentration of 50 mg/ml. Yazd EO showed the strongest antimicrobial activity, particularly against Gram-positive bacteria, with a halo diameter of 22.5 mm. In contrast, the Kerman EO showed the least amount of antimicrobial activity against Escherichia coli, with a halo diameter of 11.5 mm. Kerman EO had the highest antioxidant activity, with 93.9393%. The Ferula EO has the ability to inhibit DPPH radicals and demonstrated activity against both Gram-positive and Gram-negative bacteria, making it a strong antioxidant and natural preservative in the pharmaceutical industry.

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Volume & Issue: Articles in Press / Accepted Manuscript

Voltammetric Sensor for Acyclovir Determination Based on MoSe2/rGO Nanocomposite Modified Electrode

Abstract

Synthesis, Molecular Docking, and Anticancer Evaluation of New Azo-Based Sulfonamides against MCF 7 Human Breast Cancer Cell Line

Abstract

Zinc Alginate Beads as an Effective Biosorbent for the Removal of Eosin-B from Aquatic Solutions: Equilibrium, Kinetics, and Thermodynamic Behaviors

Abstract

Chemical Composition, Antioxidant Properties, and Antimicrobial Activity of Ferula Assa-foetida L. Essential Oil against Pathogenic Bacteria

Abstract